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Sr9011 High Purity Fitness Sarms Powder
- May 12, 2018 -

Pharmaceutical Raw Material Fitness Nutrition Sr9011 for Muscle Fitness

Sarms Powder Sr9011 High Purity for Fitness

High Quality Safe Delivery Weight Loss Raw Sarms Powder Sr9011

 

high quality Safe Delivery Weight Loss Raw Sarms powder Sr9011 

 

SR9011 

Synonyms: Ethyl-3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)pyrrolidine-1-carboxylate

SR9011 CAS No.: 1379686-30-2

SR9011 Molecular formular: C20H24ClN3O4S

SR9011 Molecular Weight: 437.94

SR9011 Appearance: White powder

SR9011 Purity: 99%

SR9011 Application: SR9011 increase exercise endurance and loss weight.

SR9011 Usage:reduce mass fat

SR9011 Packing:1kg/foil bag

Sr9011 Description:

SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.

SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.

 

SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV ERB α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.