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Thymosin Peptides Lyophilized Polypeptide Hormone Powder Α1 Alpha 1 Beta 4 2mg for Muscle Repair

Thymosin hormone Quick Details : Product Name: Thymosin alpha 1 Other Name : Thymosin Alpha 1 Acetate Synonyms:...

Product Details

Thymosin Peptides Lyophilized Polypeptide Hormone Powder Α1 Alpha 1 Beta 4 2mg for Muscle Repair

Thymosin hormone Quick Details :

 

Product Name: Thymosin alpha 1

Other Name : Thymosin Alpha 1 Acetate

Synonyms: ACETYL-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN;AC-SDAAVDTSSEITTKDLKEKKEVVEEAEN;AC-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN;AC-SER-ASP-ALA-ALA-VAL-ASP-THR-SER-SER-GLU-ILE-THR-THR-LYS-ASP-LEU-LYS-GLU-LYS-LYS-GLU-VAL-VAL-GLU-GLU-ALA-GLU-ASN-OH;THYMOSIN A1;THYMOSIN A1 BOVINE;THYMOSIN ALPHA 1;THYMOSIN ALPHA1 BOVINE

CAS: 62304-98-7

MF: C129H215N33O55

MW: 3108.28

Specification : 10mg/vial

Usage : Thymosin Alpha-1 is mainly used for the treatment of chronic hepatitis B immune strengthening agent.  Thymosin α1 is believed to be a major component of Thymosin Fraction 5 responsible for the activity of that preparation in restoring immune function in animals lacking thymus glands. It has been found to enhance cell-mediated immunity in humans as well as experimental animals.

 

Thymosin Hormone Description :

 

Thymosin α1 is a peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene. Thymosin Alpha-1 is a component of Thymosin Fraction 5 responsible for restoring immune function in animals lacking thymus glands.


It had been the peptide produced with the Thymosin Small percentage Five. Not likewhich have been genetically as well as chemically not relatedwill be developed as a 28-amino p peptide fragment at a lengthier, 113-amino chemical p forerunner,prothymosin leader. Studies have shown it all to increase cell-mediated defense within fresh critters as well as investigation subjects.


As of 2009enables inside Thirty-five under-developed or simply creating areas to the remedy for Hepatitis N together with H, which is furthermore employed to improve the the immune system effect within the therapy for alternative disorders.


Many myeloma (Millimeter) is seen as an the accumulation of monoclonal plasma tv's cellular material in the structure marrow to result in many protected adjustments in affected individualsis a thymin peptide that is connected to immuno-stimulating attributes. Furthermore, this particular peptide puts anti-tumor effects in a number many forms of cancer kinds. Beneficial effects involvingsupervision have also been found about defense reconstitution soon after hematopoietic stem mobile hair loss transplant (HSCT), a present therapy modality around hematological malignancies such as Millimeter. In this particular research, most of us observed modest lowering of the actual spreading for murine in addition to person's Millimeter mobile phone outlines inside presence ofduring vitro. Yet, utilizing two immunocompetent murine MM models (5TGM1 and also MOPC315.BM), we all wouldn't discover virtually any effect connected withadministration with Millimeter enhance vivo. Furthermore, absolutely no benefits connected withtreatment ended up found for lymphocyte immune reconstitution soon after transfusion involving man hematopoietic come cellular material straight into immunodeficient these pests. In conclusion, regardless of point results ofupon people Millimeters wireless collection expansion throughoutdid not have to generate anti-myeloma effects during vivo in the two murine designs tried. Moreoverfailed to boost exempt healing inside a xenogeneic HSCT design.


Thymosin alpha 1 AND Thymosin beta 4 :

 

Thymosin alpha 1 and thymosin beta 4 were first isolated from thymosin fr. 5 and have demonstrated biological activities on the immune system. They are chemically distinct and differ in their immunological activity profiles. The levels of thymosin alpha 1 and thymosin beta 4 were assessed by radioimmunoassay in the same serum samples. Normal thymosin alpha 1 levels were 670 +/- 163 pg/ml for males and 652 +/- 162 pg/ml for females. Normal thymosin beta 4 levels were 974 +/- 400 ng/ml for males and 889 +/- 345 ng/ml for females. No correlation between the levels of the peptides in serum from normal donors was observed. Although many samples of serum from neonates (cord blood), homosexuals and AIDS patients had elevated levels of one or both peptides, no correlation between the two peptides was found. Of potential significance is the observation that while thymosin alpha 1 and beta 4 are elevated in many individuals with AIDS (57 and 48% respectively), the individuals with AIDS related immune dysfunctions had predominantly elevated thymosin alpha 1 (54 vs 15%). These studies suggest that serum levels of the two peptides are modulated separately and that both are of potential value in defining the risk of individuals for developing AIDS.

 

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