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Polypeptide MT-1 Melanocyte Stimulating Hormone Lyophilized Powder Injections Peptides Melanotan-1 10mg for Skin Tanning

Melanotan-1 Quick Details : MT 1 Model No.: Melanotan I 10mg/vial, 100vial/kit Melanotan Export Markets: Global Melanotan I Product Description Melanotan I CAS: 75921-69-6 Formula: C78H111N21O19 Chain: AC-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-PRO-Val-NH2 Appearance: Sterile Filtered...

Product Details

Polypeptide MT-1 Melanocyte Stimulating Hormone Lyophilized Powder Injections Peptides Melanotan-1 10mg for Skin Tanning

Melanotan-1 Quick Details :


MT 1 Model No.: Melanotan I 10mg/vial, 100vial/kit
Melanotan Export Markets: Global
Melanotan I  Product Description
Melanotan I
CAS: 75921-69-6
Formula: C78H111N21O19
Chain: AC-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-PRO-Val-NH2
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder
Purity(by HPLC): >99.00%~99.90%
Total Impurities(by HPLC): 1.00%~0.05%
Single Impurity(by HPLC): <0.50%~0.08%
Origin: China (Mainland)
Storage conditions: A viod shunshine and keeping stoppered 

Usage : a peptide process for pigmentation of the skin .

 

Melanotan-1 Description :

 

MT-1 (or Melanotan I, or Afamelanotide, or CUV-1647) is a synthetic analog of peptides nature of endogenous melanocortin peptide alpha-melanocyte stimulating hormone. It has hormones nature as well as common proteins features, its molecular weight/mass is 1646.88 and its molecular formula is C78H111N21O19.

 

Afamelanotide was specifically developed by American scientists LED by V . Hruby in 1991 as a possible research compound that can be used against skin cancer by stimulating tanning system which in own turn would generate protective natural tan during melanogenesis.

 

So that synthetic analog was created to determine if it can show the same effect and stimulate melanocytes to produce and release melanin to protect skin from UV. Most of studies and trials were conducted in United States and Australia.

 

Developed research compound is quite stable cyclic form of original hormone but specifically has much longer half-life period. It works as agonist of specific melanocortin receptor and possesses such property as being selective and thus it promotes increased level of eumelanin above usual pheomelanin, which provides higher efficacy of photoprotection abilities.

 

Melanotan-1 Application :

 

Start with a dose of 1mg daily for the first two or three days and, if level of side effects permit, look to  increase dosage by 0.25mg every day over the next several days until you reach a daily dosage of  2-3mg. This level should be adequate for most users, though some may wish to increase yet further,  perhaps as high as 5mg daily in order to achieve a very deep tan. A maintenance phase as described above is then used.

 

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction,

 

Melanotan-has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

 

Both MT and MT II are currently supplied as white lyophilised powder contained in a sealed multi-use vial. The peptide is susceptible to temperature degradation and should be shipped preferably with an ice pack though contrary to popular belief, the rate of degradation is very slow (weeks) in its powder form, so there's no need to be alarmed if yours wasn't shipped in this manner or you are unable to collect your package from a depot for a day or two. Once delivered, the powder is best stored in a freezer, or refrigerated if this is not possible.

 

To prepare for injection, it must be reconstituted with bacteriostatic water. You may use anything between 1ml and 5ml of water for your vial. Dependant upon the amount of water used will determine the concentration of your solution. For example, a 10mg vial of Melanotan II mixed with 1ml of water will provide a solution of 10mg per 1ml (10mg/ml). This means that a 1mg dose will require a shot of 0.1ml. Bearing in mind that the recommended starting dose is 0.25mg, using the example above, the actual volume of the shot would be 0.025ml (¼ of 1 tenth of a ml). This is a very small volume and very difficult to accurately dose even with a 0.5ml insulin syringe. Therefore, at least until your dosages have increased, it is suggested that you use more water for your vial.

 

An example of a good solution would be to mix 10mg of Melanotan II powder with 4ml of bacteriostatic water. This now provides:

10mg/4ml or 1mg/0.4ml or 0.25mg/0.1ml

0.1ml can be accurately measured using a 0.5ml or 1ml syringe.

Obviously, as your dosages become higher, you may dilute subsequent vials with lower amounts of water to reduce the volume of each shot. I would recommend that when you are using a dosage of 1mg, you reconstitute the vial with 1ml or 2ml of water so that each shot will be 0.1ml or 0.2ml respectively.

 

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